"Fulgent Genetics, Fulgent Genetics"[submitter] AND "CAST"[gene] - ClinVar

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 354638	NM_000439.5(PCSK1):c.2137C>T (p.Leu713Phe)	PCSK1, CAST +1 more (L713F +1 more)	Single nucleotide variant (missense variant)	Monogenic Non-Syndromic Obesity +2 more	GUncertain significance
Select item 431898	NM_000439.5(PCSK1):c.1387G>A (p.Glu463Lys)	CAST, LOC101929710 +1 more (E463K +1 more)	Single nucleotide variant (missense variant)	Body mass index quantitative trait locus 12 +2 more	GConflicting classifications of pathogenicity
Select item 906972	NM_000439.5(PCSK1):c.541T>C (p.Tyr181His)	CAST, LOC101929710 +1 more (Y134H +1 more)	Single nucleotide variant (missense variant)	PCSK1-related condition +2 more	GUncertain significance
Select item 736176	NM_000439.5(PCSK1):c.352C>T (p.Leu118=)	CAST, LOC101929710 +1 more	Single nucleotide variant (synonymous variant)	Body mass index quantitative trait locus 12 +3 more	GLikely benign
Select item 791137	NM_001750.7(CAST):c.1207G>C (p.Ala403Pro)	CAST (A266P +16 more)	Single nucleotide variant (missense variant +1 more)	not provided +1 more	GBenign
Select item 1614516	NM_001750.7(CAST):c.1441G>A (p.Ala481Thr)	CAST (A326T +16 more)	Single nucleotide variant (missense variant +1 more)	Peeling skin-leukonuchia-acral punctate keratoses-cheilitis-knuckle pads syndrome +1 more	GBenign

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